You can run pretty much anything on Cat5, VGA, Usb, Sound Signals, S-Video and so on.

i decided to use a Cat5 to run a Usb connection over at least 25′, I’ve been searching a little over the web and I found a couple of ideas to connect Usb peripherals over Cat5 successfully and I went over the subject, but I realize that i didn’t want to cut the cat5 and solder the usb connections to the cable, so I decide to build a couple of Usb dongles (female and male) to cat5 and the cool thing is that they can be used on existing Ethernet network wall connections as well

Materials:
2 Ethernet Hubs (8pin RJ45 – salvaged from network cards)
1 Usb Male Plug Type A (any standard Usb cable)
1 Usb Female Plug Type A (from a Pc)
Solder Gun, wire and electric tape.
and of course a CAT5 Ethernet Cable

Instructions:
The hardest part was desoldering the Hubs from the salvaged PCB board, after that it was just a matter of selecting which cables of the CAT5 use to solder the Usb plugs and the RJ45 Hubs.

I select the pins in the following order:

RJ45 hub = USB plug
pin No. 2 = Green Cable
pin No. 4 = White Cable
pin No. 6 = Black Cable-Ground
pin No. 8 = Red Cable

These USB extenders work, for most part… But they are extremely vulnerable to EMI noise. When my A/C kicks in a different part of the house, all USB devices behind this extender disconnect and re-connect. Also, this extender does not work at all with my webcam, and works very slowly with my scanner. I think it’s only good for extending keyboards, mice, and other low-bandwidth peripherals.